Ravi Radhakrishnan
University of Pennsylvania, USA
Title: Guiding Precision and Personalized Oncology using Multiscale Computational Models
Biography
Biography: Ravi Radhakrishnan
Abstract
This talk will focus on clinical paradigms of oncogene driven tumors as well as tumors of the soft tissue and the importance of developing quantitative models in understanding disease progression, the effect of tumor microenvironment, while taking individual molecular profiles from patients into consideration. In contrast to data driven models which are statistical and extrapolative, we show the true predictive power of mechanistic models in uncovering patient response to disease progression and drug sensitivity in human cancers including the case of pediatric neuroblastoma.