Soad Jaouni
King Abdulaziz University, Saudi Arabia
Title: Novel Methodology of Detecting Minimal Residual Disease in Acute Leukemia by Using FTIR Spectroscopy
Biography
Biography: Soad Jaouni
Abstract
Previously examined the potential of conventional Fourier transform infrared spectroscopy (FTIR) in an attempt to detect specific biomarkers for discrimination between disease free and acute leukemia bone marrow samples.
AIM: To assess the efficacy in detecting minimal residual disease in acute leukemia by FTIR.
Case report, to predict early relapse, and distinguish disease free in remission (control) bone marrow samples, four bone marrow samples were obtained from an 11-year-old boy diagnosed as acute leukemia. Samples (1) and (2) for the patient in remission as diagnosed clinically and laboratory examination free, sample (3) diagnosed relapse in CNS, while sample (4) was taken post-chemotherapy induction.