Sanjay Mishra
King George's Medical University, India
Title: Incidence of bone marrow infiltration and hematological profile in patients of neuroblastoma
Biography
Biography: Sanjay Mishra
Abstract
Neuroblastoma is one of the most common malignant neoplasms of infancy. The tumour frequently metastasizes to bone marrow. Therefore bone marrow examination is regularly done for staging of the disease. In our study we analyzed 32 cases of neuroblastoma for bone marrow infiltration and correlation was made with their clinical parameters and their hematological profile. The age of these patients ranged from six months to 10.6 years. Male to female ratio was 2.3:1. Of these 18 (56.25) cases showed infiltration with the neoplastic cells. Of these, 12 cases (75%) were less than five years of age. There was a male preponderance with male: female ratio of 4:1 in involved cases. The patients who showed infiltration in the marrow had anemia, leucopenia and thrombocytopenia. 75% of these patients showed leukoerythroblastic picture. 12/18 cases showed rosette formation at some place on the smear.